Open AccessPurely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide
Author(s) -
S. Radhakrishnan,
Rajagopal Ramachandran,
Gnanasekaran Rajangam,
Navya Donaparthi
Publication year - 2015
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.169743
Subject(s) - medicine , langerhans cell histiocytosis , etiology , thalidomide , chin , scalp , dermatology , presentation (obstetrics) , histiocytosis , disease , pathology , immunology , surgery , multiple myeloma , anatomy
Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans' cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide.