Open AccessAn atypical presentation of antiphospholipid antibody syndrome
Author(s) -
Deepti Celestine D'Souza,
D Sukumar,
M Ramesh Bhat,
MK Srinath
Publication year - 2015
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.160258
Subject(s) - medicine , livedo reticularis , antiphospholipid syndrome , pyoderma gangrenosum , presentation (obstetrics) , dermatology , thrombosis , venous thrombosis , pathology , surgery , disease
Cutaneous manifestations in antiphospholipid antibody syndrome (APS) though common, are extremely diverse and it is important to know which dermatological finding should prompt consideration of antiphospholipid syndrome. The cutaneous manifestations of APS vary from livedo reticularis to cutaneous necrosis, and systemic involvement is invariably an accomplice in APS. Cutaneous ulcers with sharp margins can be seen in APS and they are usually seen on the legs. This case had an atypical presentation, as the initial presentation was painful necrotic ulcers over the legs, which resembled pyoderma gangrenosum and she had no systemic manifestations. There was no history of any arterial or venous thrombosis or any abortions. Antiphospholipid syndrome can be tricky to diagnose when cutaneous lesions are atypical. Nonetheless, it is very important to pin down this syndrome early due to its systemic complications.