Open AccessAssociation of polymorphisms in angiotensin-converting enzyme gene with gestational diabetes mellitus in Indian women
Author(s) -
Parul Aggarwal,
Nutan Agarwal,
Nibhriti Das,
Krishna Dalal
Publication year - 2016
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.174006
Subject(s) - haplotype , gestational diabetes , single nucleotide polymorphism , snp , medicine , genotype , angiotensin converting enzyme , diabetes mellitus , allele , type 2 diabetes mellitus , genetics , endocrinology , biology , gene , pregnancy , gestation , blood pressure
Numerous genes have been reported in relation with gestational diabetes mellitus (GDM), but the findings were not consistently replicated across populations, or there have been no detailed studies on them. Previous literatures suggested that, out of all angiotensin converting enzyme (ACE) gene polymorphisms, only ACE insertion/deletion (I/D) gene polymorphism has a strong association with GDM in Asian Indian women.