Open AccessPlasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
Author(s) -
Zeeba S Jairajpuri,
Safia Rana,
Manal Ashraf Ali,
Sujata Jetley
Publication year - 2015
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.165368
Subject(s) - urothelial carcinoma , immunohistochemistry , differential diagnosis , pathology , carcinoma , transitional cell carcinoma , medicine , bladder cancer , cancer
Plasmacytoid carcinoma of the urinary bladder or plasmacytoid urothelial carcinoma (PUC) is rare and only recently described a histological variant of transitional cell carcinoma. The morphological resemblance of PUC to other malignancies is a source of diagnostic dilemmas and often misdiagnosis. Immunohistochemistry plays a pivotal role in narrowing the differential diagnosis and reaching to a conclusive diagnosis. A diagnosis of PUC usually carries a dismal prognosis. Hence, correct diagnosis is important. We report here a 52-year-old male with a plasmacytoid variant of urothelial carcinoma.