Open AccessA comparative study of serum aminotransferases in chronic kidney disease with and without end-stage renal disease: Need for new reference ranges
Author(s) -
Lopamudra Ray,
Saurav Narayan Nanda,
Anirban Chatterjee,
Rajlaxmi Sarangi,
Satyaki Ganguly
Publication year - 2015
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.149232
Subject(s) - medicine , kidney disease , end stage renal disease , gastroenterology , renal function , alkaline phosphatase , renal osteodystrophy , disease , hemodialysis , liver disease , endocrinology , enzyme , biology , biochemistry
Hepatic diseases are common among chronic kidney disease patients and liver function tests particularly serum liver enzymes play an important role in diagnosing and monitoring these patients. Serum aminotransferase levels commonly fall near the lower end of the range of the normal values in patients of chronic kidney disease (CKD). High-levels of serum alkaline phosphatase (ALP) can occur in these patients due to renal osteodystrophy. Thus, the recognition of liver damage in these patients is challenging.