Open AccessExtranodal anaplastic large cell lymphoma mimicking sarcoma: A report of an interesting case
Author(s) -
Zeeba S Jairajpuri,
Safia Rana,
Shaan Khetrapal,
Majid Ahmed Talikoti,
Sujata Jetley
Publication year - 2014
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.140741
Subject(s) - anaplastic large cell lymphoma , cd30 , lymphoma , pathology , anaplastic lymphoma kinase , immune system , sarcoma , medicine , biology , cancer research , immunology , malignant pleural effusion , lung cancer
Lymphomas are malignancies of the lymphoid tissues involving cells of the immune system. Primary systemic anaplastic large cell lymphoma (ALCL) represents an aggressive lymphoma characterized by neoplastic proliferation of lymphoid cells with an anaplastic appearance. Large pleomorphic cells are "hallmark" cells with horseshoe-shaped or kidney-shaped nuclei and a constant expression of the CD30 molecule on all neoplastic cells. There is a vast morphological spectrum posing a challenge to pathologists in the diagnosis of ALCL.