Open AccessInhibition of biofilm formation and lipase in Candida albicans by culture filtrate of Staphylococcus epidermidis in vitro
Author(s) -
Sayan Bhattacharyya,
Prashant Gupta,
Gopa Banerjee,
Amita Jain,
Mastan Singh
Publication year - 2014
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.140721
Subject(s) - microbiology and biotechnology , candida albicans , staphylococcus epidermidis , biofilm , lipase , corpus albicans , yeast , staphylococcus aureus , in vitro , biology , chemistry , food science , enzyme , bacteria , biochemistry , genetics
Candida spp. are fourth most common cause of bloodstream infection in developed countries and emerging agents of fungemia in developing countries, with considerable attributable mortality. Candidemia is associated with the formation of complex, structured microbial communities called biofilms. Biofilm formation makes treatment difficult due to improper drug penetration and factors like high cost and adverse effects of antifungal drugs available. Hence, low-cost alternatives are urgently required to treat device-associated invasive candidiasis.