Open AccessA case of rapid progression of postoperative hyperthermia: Dantrolene or not dilemma?
Author(s) -
Marzieh R. Honardar,
J.H.G. Rubio,
Sanjay M. Bhananker
Publication year - 2016
Publication title -
international journal of critical illness and injury science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.274
H-Index - 12
eISSN - 2231-5004
pISSN - 2229-5151
DOI - 10.4103/2229-5151.195451
Subject(s) - medicine , dantrolene , hypermetabolism , malignant hyperthermia , rhinovirus , respiratory acidosis , lactic acidosis , anesthesia , pediatric intensive care unit , intensive care medicine , intensive care unit , acidosis , respiratory system , calcium
Malignant hyperthermia (MH) is an extremely rare and life-threatening differential diagnosis of postoperative fever. We present an 8-month-old child scheduled for elective outpatient procedure who rapidly developed high fever, tachycardia, and respiratory acidosis shortly after transfer to the postanesthesia care unit. MH hotline expert recommended administering dantrolene, but there was no evidence of hypermetabolism or lactic acidosis. The patient remained clinically stable after admission to the pediatric intensive care unit and was discharged home the next day. The fever was likely due to viral infections as confirmed by a positive result of viral polymerase chain reaction for human metapneumovirus and rhinovirus/enterovirus.