Open AccessEvaluation of circulating haematopoietic progenitor cells in patients with Trauma Haemorrhagic shock and its correlation with outcomes
Author(s) -
Manoj Kumar,
Sanjeev Bhoi,
Arulselvi Subramanian,
Vineet Kumar Kamal,
Sujata Mohanty,
D. N. Rao,
Sagar Galwankar
Publication year - 2016
Publication title -
international journal of critical illness and injury science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.274
H-Index - 12
eISSN - 2231-5004
pISSN - 2229-5151
DOI - 10.4103/2229-5151.183016
Subject(s) - medicine , bone marrow , progenitor cell , shock (circulatory) , haematopoiesis , prospective cohort study , hematology , peripheral blood , bone marrow failure , gastroenterology , pathology , stem cell , genetics , biology
Haemorrhagic shock accounts up to 50% of early trauma deaths. Hematopoietic failure has been observed in experimental animals and human following shock and injury. One of the facets of bone marrow failure is multiple organ dysfunction syndrome and is commonly seen in patients recovering from severe trauma and hemorrhagic shock. Bone Marrow (BM) dysfunction is associated with mobilization of hematopoietic progenitor cells (HPCs) into peripheral blood. Present study explored the association of peripheral blood hematopoietic progenitor cells (HPCs) with mortality in trauma haemorrhagic shock patients (T/HS).