Open AccessBroadening of the red blood cell distribution width is associated with increased severity of illness in patients with sepsis
Author(s) -
Nader Mahmood,
Jimmy Mathew,
Balwinder Kang,
Vincent A. DeBari,
Muhammad Anees Khan
Publication year - 2014
Publication title -
international journal of critical illness and injury science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.274
H-Index - 12
eISSN - 2231-5004
pISSN - 2229-5151
DOI - 10.4103/2229-5151.147518
Subject(s) - medicine , red blood cell distribution width , sepsis , confounding , odds ratio , apache ii , cohort , retrospective cohort study , biomarker , severity of illness , critical illness , gastroenterology , critically ill , intensive care unit , biochemistry , chemistry
Sepsis is a pro-inflammatory state caused by systemic infection. As sepsis progresses, multiple organ systems become affected with subsequent increase in mortality. Elevated red cell distribution width (RDW) has been seen with changes of other inflammatory markers and thus could potentially serve as a means of assessing sepsis severity. In this study, we examine the association of RDW with APACHE II score and in-hospital mortality.