Open AccessPolymerase chain reaction detection and inducible nitric-oxide synthase expression of Leishmania major in mice inoculated by two different routes
Author(s) -
Amal Mahmoud,
Rasha Adel,
Hanan E. M. Eldeek,
Haiam Mohamed Mahmoud Farrag,
Rania Makboul
Publication year - 2016
Publication title -
tropical parasitology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.418
H-Index - 11
eISSN - 2229-7758
pISSN - 2229-5070
DOI - 10.4103/2229-5070.175088
Subject(s) - histopathology , spleen , nitric oxide synthase , lymph , polymerase chain reaction , inoculation , pathology , lymph node , nitric oxide , biology , microbiology and biotechnology , immunology , medicine , gene , endocrinology , biochemistry
Leishmania major needs a sensitive and specific method for proper diagnosis. This study aims to study the course and histopathology of L. major in certain tissues of experimentally infected BALB/c mice after subcutaneous (sc) and intraperitoneal (ip) inoculation.