Open AccessPerformance of polymerase chain reaction for the diagnosis of cystic echinococcosis using serum, urine, and cyst fluid samples
Author(s) -
Chaya,
Subhash Chandra Parija
Publication year - 2014
Publication title -
tropical parasitology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.418
H-Index - 11
eISSN - 2229-7758
pISSN - 2229-5070
DOI - 10.4103/2229-5070.129164
Subject(s) - echinococcus granulosus , cystic echinococcosis , polymerase chain reaction , cyst , serology , antigen , urine , echinococcosis , pathology , medicine , hydatid cyst , biology , antibody , immunology , gene , zoology , biochemistry
Cystic echinococcosis (CE) is a chronic zoonosis which presents with variable clinical manifestations. Currently the diagnosis of this disease is based on radiological findings and serological tests which lack specificity. Although antigen detection from the cyst fluid is the most specific, it is seldom done due to the complications involved. Detecting the presence of Echinococcus granulosus specific deoxyribonucleic acid (DNA) by the polymerase chain reaction (PCR) could provide a definitive diagnosis of CE.