Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against Mycobacterium | Zendy

Shunsuke Aoki | Zendy; Yuji Koseki | Zendy; Hironori Kanetaka | Zendy; Joji Tsunosaki | Zendy; Hélène MunierLehmann | Zendy

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Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against Mycobacterium

Author(s) -

Shunsuke Aoki,

Yuji Koseki,

Hironori Kanetaka,

Joji Tsunosaki,

Hélène MunierLehmann

Publication year - 2017

Publication title -

international journal of mycobacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 20

eISSN - 2212-554X

pISSN - 2212-5531

DOI - 10.4103/2212-5531.201893

Subject(s) - mycobacterium smegmatis , pharmacophore , in silico , mycobacterium tuberculosis , potency , chemistry , growth inhibition , mycobacterium , biochemistry , ic50 , structure–activity relationship , microbiology and biotechnology , pharmacology , stereochemistry , biology , tuberculosis , in vitro , bacteria , medicine , genetics , pathology , gene

Mycobacterium tuberculosis thymidine monophosphate kinase (mtTMPK) is a potential enzymatic target for the treatment of tuberculosis (TB).

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