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Radiographically Occult Latent Radiogenic Osteosarcoma Uncovered on Tc-99m Methylene-diphosphonate Bone Scintigraphy
Author(s) -
Prashant Jolepalem,
Raymond Y. Yeow,
Diane Cosner,
John P. Seitz
Publication year - 2013
Publication title -
journal of clinical imaging science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.279
H-Index - 18
eISSN - 2156-7514
pISSN - 2156-5597
DOI - 10.4103/2156-7514.120786
Subject(s) - medicine , occult , bone scintigraphy , technetium , osteosarcoma , scintigraphy , radiology , nuclear medicine , radiogenic nuclide , prostate cancer , cancer , pathology , isotope , alternative medicine , physics , quantum mechanics
We present a case of a 70-year-old male who was referred for a technetium-99m methylene-diphosphonate bone scan for mild left hip pain and an elevated alkaline phosphatase level of 770 units/L. No additional information was provided and the patient′s history was limited due to a language barrier. We were able to ascertain that the patient had a remote history of prostate cancer, which had been treated with radiation. Originally, we felt the bone scan was compatible with Paget′s disease; however, further work-up revealed the presence of osteosarcoma, which was potentially radiation-induced

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