Open AccessTight glycemic control and cardiovascular effects in type 2 diabetic patients
Author(s) -
Latha Subramanya Moodahadu,
Ruchi Dhall,
Abdul Hamid Zargar,
Sudhakar Bangera,
Lalitha Ramani,
Ramesh Katipally
Publication year - 2014
Publication title -
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Language(s) - English
Resource type - Journals
eISSN - 0976-5123
pISSN - 1995-705X
DOI - 10.4103/1995-705x.151084
Subject(s) - medicine , glycemic , dyslipidemia , hypoglycemia , diabetes mellitus , adverse effect , type 2 diabetes mellitus , oral hypoglycemic agents , intensive care medicine , type 2 diabetes , endocrinology
Diabetes Mellitus (DM) with poor glycemic control is one of the leading causes for cardiovascular mortality in diabetic patients. Tight glycemic control with glycosylated haemoglobin of <7 gms% is recommended as a routine and < 6.5 gms% is recommended for young and newly diagnosed diabetics. Treatment goal aims at achieving near normal blood glucose level, and directed at management of other co morbid conditions such as obesity, hypertension and dyslipidemia. Oral hypoglycemic agents are the preferred drugs, alone or in combination. Preference for glitazones is declining due to the increasing evidences of associated adverse events. Gliptins appear as promising agents with lesser tendency to cause hypoglycemia, but their long term safety and efficacy is yet to be established. We emphasize the role of preventive measures in prediabetics and in established DM, treatment should be individualized and customized to minimize hypoglycemic effects and to retain quality of life.