Open AccessRecurrent myocardial infarction in a case of congenital Afibrinogenemia
Author(s) -
Soumya Patra,
Babu Reddy,
C.M. Nagesh,
B.C. Srinivas,
CN Manjunath
Publication year - 2014
Publication title -
heart views
Language(s) - English
Resource type - Journals
eISSN - 0976-5123
pISSN - 1995-705X
DOI - 10.4103/1995-705x.132141
Subject(s) - medicine , afibrinogenemia , myocardial infarction , presentation (obstetrics) , surgery , major bleeding , pediatrics , fibrinolytic therapy , thrombosis , cardiology , fibrinogen
Afibrinogenemia is a rare autosomal recessive bleeding disorder with an estimated prevalence of 1:1,000,000. Usual presentation of this disorder is spontaneous bleeding, bleeding after minor trauma and excessive bleeding during interventional procedures. Paradoxically, few patients with afibrinogenemia may also suffer from severe thromboembolic complications. The management of these patients is particularly challenging because they are not only at risk of thrombosis but also of bleeding. We are presenting a case of 33-year-old male patient of congenital afibrinogenemia who had two episodes myocardial infarction in a span of two years. The patient was managed conservatively with antiplatelet therapy and thrombolytic therapy was not given due to high risk for bleeding.