Open AccessStatin intolerance because of myalgia, myositis, myopathy, or myonecrosis can in most cases be safely resolved by vitamin d supplementation
Author(s) -
Maksim Khayznikov,
Kallish Hemachrandra,
Ramesh Pandit,
Ashwin Kumar,
Ping Wang,
Charles J. Glueck
Publication year - 2015
Publication title -
north american journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2250-1541
pISSN - 1947-2714
DOI - 10.4103/1947-2714.153919
Subject(s) - myalgia , medicine , myopathy , myositis , vitamin d and neurology , statin , gastroenterology , vitamin , vitamin d deficiency , endocrinology
Low serum vitamin D can cause myalgia, myositis, myopathy, and myonecrosis. Statin-induced myalgia is a major and common cause of statin intolerance. Low serum vitamin D and statins, additively or synergistically, cause myalgia, myositis, myopathy, and/or myonecrosis. Statin-induced myalgia in vitamin D deficient patients can often be resolved by vitamin D supplementation, normalizing serum vitamin D levels.