
Medulloblastoma in childhood-King Edward Memorial hospital surgical experience and review: Comparative analysis of the case series of 365 patients
Author(s) -
Dattatraya Muzumdar,
Amit Ajit Deshpande,
Ratnesh Kumar,
Ankur Sharma,
Naina Goel,
Nitin Dange,
Abhida Shah,
Atul Goel
Publication year - 2011
Publication title -
journal of pediatric neurosciences
Language(s) - English
Resource type - Journals
eISSN - 1998-3948
pISSN - 1817-1745
DOI - 10.4103/1817-1745.85717
Subject(s) - medicine , medulloblastoma , headaches , papilledema , surgery , posterior fossa , pediatrics , pathology
Medulloblastoma is one of the most common posterior fossa tumors in childhood. The treatment-related side effects as well as predictive outcome still remain as a major challenge. The improved understanding of the disease and advances in molecular biology is changing the treatment paradigms from Chang's staging system to molecular risk stratification. However, surgery still remains as an important mainstay of therapy and is formidable. The role of radical surgery has always been a crucial factor in the outcome of these patients, the best survival being reported in patients who had total excision of the tumor and with no metastasis.