Open AccessEffect of nimodipine on morphine-related withdrawal syndrome in rat model: An observational study
Author(s) -
Pranaya Mishra,
Mayadhar Barik,
Subrata Basu Ray
Publication year - 2017
Publication title -
journal of pediatric neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
eISSN - 1998-3948
pISSN - 1817-1745
DOI - 10.4103/1817-1745.205652
Subject(s) - nimodipine , morphine , medicine , anesthesia , (+) naloxone , bolus (digestion) , pharmacology , opioid , calcium , receptor
To observe the effect of L-type calcium channel blocker like nimodipine on morphine's withdrawal when it was administered continuously along with morphine versus a single bolus dose of nimodipine, which was administered at the end of the experiment before the precipitation of withdrawal reaction in morphine-dependent rats.