Open AccessNeuroblastoma presenting as opsoclonus-myoclonus: A series of six cases and review of literature
Author(s) -
Jagdish Prasad Meena,
Rachna Seth,
Biswaroop Chakrabarty,
Sheffali Gulati,
Sandeep Agrawala,
Priyanka Naranje
Publication year - 2016
Publication title -
journal of pediatric neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
eISSN - 1998-3948
pISSN - 1817-1745
DOI - 10.4103/1817-1745.199462
Subject(s) - medicine , neuroblastoma , myoclonus , series (stratigraphy) , pediatrics , psychiatry , genetics , biology , cell culture , paleontology
The opsoclonus-myoclonus ataxia syndrome (OMAS) also called "Kinsbourne syndrome" or "dancing eye syndrome" is a rare but serious disorder characterized by opsoclonus, myoclonus, and ataxia, along with extreme irritability and behavioural changes. Data on its epidemiology, clinical features, and outcome are limited worldwide. The aim of the study was to evaluate the clinical profile and outcome of children with OMAS. A retrospective data of all children presented to Pediatric oncology clinic with a diagnosis of opsoclonus-myoclonus from 2013 to 2016 were collected. 6 patients with a diagnosis of OMAS were presented over a 4-year period. All 6 cases had paraneoplastic etiology. All Children had good outcome without any relapse. Paraneoplastic opsoclonus myoclonus had a good outcome in our experience.