Open AccessEffect of therapeutic hypothermia on chromosomal aberration in perinatal asphyxia
Author(s) -
Bahubali D Gane,
S. Nandhakumar,
Vishnu Bhat,
Ramachandra Rao
Publication year - 2016
Publication title -
journal of pediatric neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
eISSN - 1998-3948
pISSN - 1817-1745
DOI - 10.4103/1817-1745.181269
Subject(s) - hypothermia , medicine , encephalopathy , asphyxia , perinatal asphyxia , peripheral blood , physiology , obstetrics , anesthesia
Perinatal asphyxia is a major cause for neonatal mortality and morbidity around the world. The reduction of O2 results in the generation of reactive oxygen species which interact with nucleic acid and make alteration in the structure and functioning of the genome. We studied the effect of therapeutic hypothermia on chromosomes with karyotyping.