Open AccessCilazapril-induced pleural effusion: A case report and review of the literature
Author(s) -
Eli̇f Küpeli̇,
Gaye Ulubay,
Sevinç Sarınç Ulaşlı,
Dalokay Kılıç
Publication year - 2010
Publication title -
annals of thoracic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.639
H-Index - 33
eISSN - 1817-1737
pISSN - 1998-3557
DOI - 10.4103/1817-1737.65043
Subject(s) - medicine , cilazapril , thoracentesis , pleural effusion , effusion , chest pain , surgery , angiotensin converting enzyme , ace inhibitor , blood pressure
We describe an unusual case of lymphocytic pleural effusion associated with the use of cilazapril, a novel angiotensin-converting-enzyme inhibitor (ACEI). An 80-year-old male was prescribed cilazapril for hypertension. He subsequently presented with right chest pain and dry cough. He was found to have a lymphocytic pleural effusion on thoracentesis. Extensive workup, including open pleural biopsy, failed to reveal the etiology of the effusion. However, soon after the withdrawal of cilazapril, his clinical symptoms improved and the effusion disappeared. ACEI-induced pleural effusion has only been rarely reported. Drug-induced pleural effusion should be considered when formulating the differential diagnosis in a patient receiving ACEI.