Open AccessMalignant fibrous histiocytoma of the skull base: A neurosurgical nuance
Author(s) -
Amit Mahore,
Raghvendra Ramdasi,
Nitin Dange,
Sridhar Epari
Publication year - 2015
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 1793-5482
DOI - 10.4103/1793-5482.154981
Subject(s) - medicine , skull , magnetic resonance imaging , histopathology , vomiting , presentation (obstetrics) , radiology , middle cranial fossa , surgery , pathology
A 69-year-old male, treated for colonic carcinoma 15 years back, presented to our services with status epilepticus. He had complaints of headache and vomiting for 7 days prior to presentation. Computed tomography and magnetic resonance imaging of the brain revealed heterogeneous, lobulated and osteolytic tumor involving middle and posterior cranial fossa. Excision of the tumor was planned in two stages. Middle fossa component was removed through right temporobasal approach. Histopathology was suggestive of malignant fibrous histiocytoma. Patient succumbed to pneumonia and septicemia in the postoperative period. Pathology, clinical features and therapeutic challenges of this clinical entity have been briefly reviewed.