Open AccessDesign, synthesis, and cytotoxicity evaluation of novel indole-acylhydrazone derivatives of 4-pyridinone as potential histone deacetylase-2 inhibitors
Author(s) -
Niloofar Naghi-Ganji,
Lotfollah Saghaie,
Farial Tavakoli,
Vajihe Azimian,
Mina Mirian,
Hajar Sirous,
Mahboubeh Rostami
Publication year - 2022
Publication title -
research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.685
H-Index - 29
eISSN - 1735-9414
pISSN - 1735-5362
DOI - 10.4103/1735-5362.355214
Subject(s) - chemistry , histone deacetylase , cytotoxicity , acetylation , histone deacetylase 2 , cell culture , docking (animal) , indole test , mtt assay , panobinostat , stereochemistry , histone deacetylase inhibitor , ic50 , histone , biochemistry , cell growth , in vitro , biology , medicine , genetics , nursing , gene