Open AccessEvaluation of the cytotoxic and apoptogenic effects of cinnamaldehyde on U87MG cells alone and in combination with doxorubicin
Author(s) -
Abbas Abbasi,
Marziyeh Hajialyani,
Leila Hosseinzadeh,
Fereshteh Jalilian,
Parichehreh Yaghmaei,
Sahar Jamshidi Navid,
Hajar Motamed
Publication year - 2020
Publication title -
research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.685
H-Index - 29
eISSN - 1735-9414
pISSN - 1735-5362
DOI - 10.4103/1735-5362.278712
Subject(s) - cytotoxic t cell , apoptosis , doxorubicin , chemistry , viability assay , pharmacology , cytotoxicity , mtt assay , ic50 , in vitro , biochemistry , biology , medicine , chemotherapy
In the present study, we tried for the first time to examine whether cinnamaldehyde (CA), with herbal nature, can be co-administrated with doxorubicin (DOX, as an anticancer drug) toward U87MG glioblastoma cells to potentiate its cytotoxic effect and overcome or reduce its side effects.