Open AccessTissue engineering for the repair of peripheral nerve injury
Author(s) -
Peixun Zhang,
Ning Han,
Yuhui Kou,
Qian Zhu,
Xiaolin Liu,
Daping Quan,
Jianguo Chen,
Baoguo Jiang
Publication year - 2019
Publication title -
neural regeneration research/neural regeneration research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.93
H-Index - 38
eISSN - 1876-7958
pISSN - 1673-5374
DOI - 10.4103/1673-5374.243701
Subject(s) - peripheral nerve injury , scaffold , regeneration (biology) , peripheral nerve , tissue engineering , medicine , nerve injury , peripheral , process (computing) , peripheral nervous system , neuroscience , computer science , biomedical engineering , anatomy , surgery , biology , central nervous system , microbiology and biotechnology , operating system
Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold material, the seed cells and various growth factors. Understanding the type of nerve injury, the construction of scaffold and the process of repair are necessary to solve peripheral nerve injury and promote its regeneration. This review describes the categories of peripheral nerve injury, fundamental research of peripheral nervous tissue engineering and clinical research on peripheral nerve scaffold material, and paves a way for related research and the use of conduits in clinical practice.