Open AccessCombination of dexmedetomidine and remifentanil for labor analgesia: A double-blinded, randomized, controlled study
Author(s) -
Waleed Abdalla,
Mona Ahmed Ammar,
Ayman I. Tharwat
Publication year - 2015
Publication title -
saudi journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 24
eISSN - 1658-354X
pISSN - 0975-3125
DOI - 10.4103/1658-354x.159470
Subject(s) - dexmedetomidine , medicine , remifentanil , double blinded , anesthesia , randomized controlled trial , surgery , propofol , sedation , alternative medicine , pathology , placebo
Satisfactory analgesia is of great importance in the labor. The clinical efficacy and side effects of remifentanil in the management of labor pain had been evaluated. Dexmedetomidine (DMET) demonstrates an antinociceptive effect in visceral pain conditions. Aims of the study were to assess whether the combination of DMET with remifentanil would produce a synergistic effect that results in lower analgesic requirements. Furthermore, whether this combination would have less maternal and neonatal adverse effects.