Open AccessA child with xeroderma pigmentosum for excision of basal cell carcinoma
Author(s) -
Sridevi M Mulimani,
Dayanand G Talikoti
Publication year - 2013
Publication title -
saudi journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 24
eISSN - 1658-354X
pISSN - 0975-3125
DOI - 10.4103/1658-354x.121050
Subject(s) - xeroderma pigmentosum , medicine , nucleotide excision repair , basal cell carcinoma , surgical excision , basal cell , dermatology , dna repair , cancer research , surgery , dna , pathology , genetics , biology
Xeroderma pigmentosum (XP) is characterized by hypersensitivity to sunlight, ocular involvement, and progressive neurological complications. These manifestations are due to a cellular hypersensitivity to ultraviolet radiation leading to a defect in repair of DNA by the process of nucleotide excision repair. Basal cell carcinoma which is rare in children can occur with XP. Though the XP induced changes are predominately dermatologic, pose several challenges in anaesthetic management. Hence, we are reporting a 9-year-old child with XP scheduled for excision of basal cell carcinoma under general anaesthesia.