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Comparison of the antiemetic effect of ramosetron with the combination of dexamethasone and ondansetron in middle ear surgery: A double-blind, randomized clinical study
Author(s) -
Sameer Desai,
M. C. B. Santosh,
Rashmi V Annigeri,
VB Santoshi,
Raghavendra Pralhada Rao
Publication year - 2013
Publication title -
saudi journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 24
eISSN - 1658-354X
pISSN - 0975-3125
DOI - 10.4103/1658-354x.115328
Subject(s) - medicine , ondansetron , antiemetic , dexamethasone , anesthesia , double blind , randomized controlled trial , surgery , vomiting , alternative medicine , pathology , placebo
Postoperative nausea and vomiting (PONV) is a frequent complication of middle ear surgery. Ondansetron has been shown to be effective for early PONV and dexamethasone has been shown to be effective for late PONV. Therefore, a combination of dexamethasone and ondansetron is commonly used for middle ear surgery. This study was conducted to compare the combination of ondansetron and dexamethasone with ramosetron for early and late PONV up to 48 h after middle ear surgery.

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