Open AccessThe Protective effect of the endoplasmic reticulum stress-related factors BiP/GRP78 and CHOP/Gadd153 on noise-induced hearing loss in guinea pigs
Author(s) -
Qiuhong Xue,
Caihong Li,
Jia Chen,
Hongmei Guo,
Dongqing Li,
Xianglei Wu
Publication year - 2016
Publication title -
noise and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.344
H-Index - 48
eISSN - 1998-4030
pISSN - 1463-1741
DOI - 10.4103/1463-1741.192481
Subject(s) - endoplasmic reticulum , chop , noise induced hearing loss , hearing loss , unfolded protein response , noise exposure , audiology , medicine , microbiology and biotechnology , biology
The audiological features and cochlear morphology of individuals with noise-induced hearing loss (NIHL) are well characterized. However, the molecular processes in the cochlea are not well understood.