Open AccessComparison of the effects of N-acetyl-cysteine and ginseng in prevention of noise induced hearing loss in male textile workers
Author(s) -
Afsaneh Doosti,
Yones Lotfi,
Abdollah Moossavi,
Enayatollah Bakhshi,
Azita Hajhossein Talasaz,
Ahmad Hoorzad
Publication year - 2014
Publication title -
noise and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.344
H-Index - 48
eISSN - 1998-4030
pISSN - 1463-1741
DOI - 10.4103/1463-1741.137057
Subject(s) - ginseng , noise induced hearing loss , hearing loss , medicine , audiology , audiometry , auditory fatigue , pure tone audiometry , noise (video) , noise exposure , alternative medicine , pathology , artificial intelligence , computer science , image (mathematics)
Previous studies revealed the role of antioxidant agents in prevention of noise induced hearing loss (NIHL). The aim of this study was to compare the protective effect of N-acetyl-cysteine (NAC) and ginseng on protection of NIHL in textile workers exposed to continuous noise in daily working. In this study, 48 participants were randomly allocated to three groups; Group I received NAC 1200 mg/day, Group II received ginseng 200 mg/day, and Group III (control group) received no supplement. Pure tone audiometry and high frequency audiometry were performed preshift before and after 14 days (on day 15). Linear regression analysis results showed reduced noise-induced temporary threshold shift (TTS) for NAC and ginseng groups at 4, 6 and 16 kHz (P < 0.001) in both ears. Furthermore, the protective effects were more prominent in NAC than ginseng. Our results show that NAC and ginseng can reduce noise induced TTS in workers exposed to occupational noise. Further studies are needed to prove antioxidants benefits in hearing conservation programs.