Open AccessLiver metastasis of lung cancer detected with similar uptake pattern on bone scintigraphy and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography: What's the pathophysiologic mechanism?
Author(s) -
Funda Üstün,
Salim Aksoy,
Burcu Dirlik Serim,
Gülay Durmuş Altun
Publication year - 2017
Publication title -
world journal of nuclear medicine
Language(s) - English
Resource type - Journals
eISSN - 1607-3312
pISSN - 1450-1147
DOI - 10.4103/1450-1147.203069
Subject(s) - medicine , diphosphonates , bone scintigraphy , fluorodeoxyglucose , scintigraphy , positron emission tomography , metastasis , nuclear medicine , calcification , radiology , bone metastasis , lung , cancer , bone resorption
Bone scintigraphy with 99m Tc diphosphonates may exhibit extraosseous lesions in addition to metastatic lesions. Multiple factors can affect extraosseous 99m Tc methylene diphosphonate (MDP) uptake. Similar uptake pattern of 99m Tc MDP and fluorine-18 fluorodeoxyglucose ( 18 F FDG) in hepatic metastasis was not already notified. In our case, initial tumor necrosis and subsequent intracellular calcification resulted in similar 99m Tc MDP and 18 F FDG accumulation in the metastatic area.