Open AccessPartial internal biliary diversion: A solution for intractable pruritus in progressive familial intrahepatic cholestasis type 1
Author(s) -
Ramaswamy Ganesh,
Suresh Narva,
Malathi Sathiyasekeran,
Priya Ramachandran
Publication year - 2011
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.80387
Subject(s) - progressive familial intrahepatic cholestasis , medicine , cholestasis , gastroenterology , cirrhosis , jaundice , surgery , liver transplantation , transplantation
Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders. Progressive familial intrahepatic cholestasis (PFIC) is an inherited disorder of impaired bile acid transport and excretion, which presents with jaundice and pruritus in the first few months of life and progresses to cirrhosis by infancy or adolescence. We report a child with PFIC type 1 who underwent internal biliary diversion for intractable pruritus and was relieved of his symptoms.