Open AccessSignificance of platelet count in esophageal carcinomas
Author(s) -
Ali Aminian,
Faramarz Karimian,
Rasoul Mirsharifi,
Abbas Alibakhshi,
Habibollah Dashti,
Yosra Jahangiri,
Sepideh Safari,
Hamid Ghaderi,
Morteza Noaparast,
Sharareh M Hasani,
Alireza Mirsharifi
Publication year - 2011
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.77245
Subject(s) - medicine , thrombocytosis , adenocarcinoma , platelet , gastroenterology , perineural invasion , esophageal cancer , cancer , esophagectomy , stage (stratigraphy) , pathology , oncology , paleontology , biology
Thrombocytosis is found to be associated with unfavorable prognosis in esophageal carcinoma. Platelets produce thymidine phosphorylase which is a platelet-derived endothelial cell growth factor with angiogenic activity. Increased platelet count may be translated into enhanced tumor growth. We examined the relation between platelet count and several prognostic variables in patients with esophageal cancer.