Open AccessSerum hyaluronic acid as a noninvasive marker of hepatic fibrosis in chronic hepatitis B
Author(s) -
Bita Geramizadeh,
Katayoun Janfeshan,
Mehdi Saberfiroozi
Publication year - 2008
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.43274
Subject(s) - medicine , hyaluronic acid , fibrosis , gastroenterology , liver biopsy , biopsy , chronic hepatitis , hepatic fibrosis , hepatitis b , hepatitis c , pathology , immunology , virus , anatomy
Chronic hepatitis B is a serious global health problem. Liver biopsy is currently recommended as the gold standard for the evaluation of the degree of fibrosis in patients with chronic hepatitis B. This procedure, however, is invasive and has potential complications. In this study, we attempted to validate the level of hyaluronic acid as a simple laboratory test to discriminate between patients with and without significant fibrosis in chronic hepatitis B.