Open AccessGastroprotective effect of an aqueous suspension of black cumin Nigella sativa on necrotizing agents-induced gastric injury in experimental animals
Author(s) -
Ibrahim A Al Mofleh,
Abdulqader A. Alhaider,
Jaber S. Mossa,
Mohammed Al-Sohaibani,
Mohammed A. Al-Yahya,
Syed Rafatullah,
Shaffi Ahamed Shaik
Publication year - 2008
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.41731
Subject(s) - nigella sativa , mucus , medicine , traditional medicine , gastric mucosa , pharmacology , thymoquinone , gastric content , antioxidant , stomach , chemistry , biochemistry , biology , ecology
Previous studies on "Black seed" or "Black Cumin" Nigella sativa (NS) have reported a large number of pharmacological activities including its anti-ulcer potential. These studies employed either fixed oil, volatile oil components or different solvent extracts. In folkloric practices, NS seeds are taken as such, in the form of coarse dry powder or the powdered seeds are mixed with water. This study examines the effect of NS aqueous suspension on experimentally induced gastric ulcers and basal gastric secretion in rats to rationalize its use by herbal and Unani medicine practitioners.