Endoscopic ultrasound and hisopathologic correlates in eosinophilic gastroenteritis

Eosinophilic gastroenteritis is a rare condition characterized by eosinophilic infiltration into any layer of stomach and intestine (mucosa, muscularis mucosa and serosa), usually in association with peripheral eosinophilia. In this case report, we present a patient with eosinophilic gastroenterocolitis who had a history of bronchial asthma and presented with abdominal pain. He was found to have peripheral eosinophilia, perforation and gangrenous bowel on performing surgery and tissue eosinophilia on histopathology examination. His endoscopic ultrasound (EUS) showed significant thickening of his antral and duodenal mucosal and submucosal layers which correlated well with the gross and microscopic pathology of the resected surgical specimen. This is the first case to demonstrate EUS abnormalities in this very rare disorder.