Open AccessThe role of leptin in non-alcoholic fatty liver disease
Author(s) -
Reda A Elbadawy,
Eman A Eleter,
Ahmed Helmy,
Abdalla S Al Ghamdi,
Ibrahim Al-Mofleh,
Faleh Z. Al Faleh,
Hussain Al Freihi,
Saleh M. Al-Amri
Publication year - 2006
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.27848
Subject(s) - medicine , leptin , steatohepatitis , steatosis , fatty liver , cirrhosis , gastroenterology , fibrosis , chronic liver disease , pathogenesis , histopathology , disease , obesity , pathology
The role of steatosis in the pathogenesis of chronic liver disease (CLD) is now believed to form part of a continuum in non-alcoholic fatty liver disease (NAFLD). One of the unconventional areas in which leptin is now receiving great attention is liver diseases. Several published studies indicate that circulating leptin is increased in patients with cirrhosis, chronic HCV, and non-alcoholic steatohepatitis (NASH).