Open AccessDiagnostic roles of calretinin in hirschsprung disease: A comparison to neuron-specific enolase
Author(s) -
Zaidoon A. Musa,
Ban Qasim,
Haider F. Ghazi,
A. Wahab A. K Al Shaikhly
Publication year - 2017
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.199118
Subject(s) - calretinin , enolase , medicine , pathology , submucosa , immunostaining , ganglion , h&e stain , lamina propria , immunohistochemistry , hirschsprung's disease , anatomy , disease , epithelium
Diagnosis of Hirschsprung's disease (HD) can be hard and requires good experience, principally for pathologists who infrequently encounter the disease. However, diagnosis is not always possible with hematoxylin and eosin (H and E) because staining has limitations in the identification of immature ganglion cells in neonates and the submucosal area.