Open AccessDesmoplasia influenced recurrence of disease and mortality in stage III colorectal cancer within five years after surgery and adjuvant therapy
Author(s) -
Maddalena Zippi,
Giorgio De Toma,
G. Minervini,
C. Cassieri,
Roberta Pica,
Diodoro Colarusso,
Simon Stock,
Pietro Crispino
Publication year - 2017
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.199114
Subject(s) - desmoplasia , medicine , adjuvant therapy , colorectal cancer , malignancy , stage (stratigraphy) , survival rate , mortality rate , cancer , surgery , oncology , biology , paleontology , pancreatic cancer
In patients with colon cancer who undergo resection for potential cure, 40-60% have advanced locoregional disease (stage III). Those who are suitable for adjuvant treatment had a definite disease-free-survival benefit. The aim of the present study was to demonstrate whether the presence of desmoplasia influenced the mortality rate of stage III colorectal cancer (CRC) within 5 years from the surgery and adjuvant therapy.