Open AccessEffect of angiotensin-converting enzyme inhibitor, lisinopril on morphological and biochemical aspects of fibrotic liver regeneration
Author(s) -
Aysha Ambreen,
Sarwat Jahan,
S. A. Malik
Publication year - 2016
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.195559
Subject(s) - lisinopril , liver regeneration , hepatocyte , medicine , hepatectomy , regeneration (biology) , alanine transaminase , endocrinology , carbon tetrachloride , hepatic stellate cell , fibrosis , angiotensin converting enzyme , pharmacology , chemistry , biochemistry , surgery , biology , blood pressure , microbiology and biotechnology , organic chemistry , resection , in vitro
Hepatic fibrosis results in defective liver regeneration following partial hepatectomy. Angiotensin converting enzyme (ACE) inhibitors can enhance liver regeneration and are also involved in the reduction of hepatic fibrosis. The present study has been conducted to evaluate the potential effect of an ACE inhibitor, lisinopril, on the morphological and biochemical aspects of fibrotic liver regeneration.