Open AccessThe relationship of circulating fetuin-a with liver histology and biomarkers of systemic inflammation in nondiabetic subjects with nonalcoholic fatty liver disease
Author(s) -
Gürkan Çelebi,
Halil Genç,
Hasan Gürel,
Erdim Sertoğlu,
Muammer Kara,
Serkan Tapan,
Cengizhan Açıkel,
Yıldırım Karslıoğlu,
Cemal Nuri Erçin,
Teoman Doğru
Publication year - 2015
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.157556
Subject(s) - medicine , insulin resistance , adiponectin , nonalcoholic fatty liver disease , steatosis , fetuin , endocrinology , inflammation , fatty liver , systemic inflammation , metabolic syndrome , gastroenterology , insulin , disease , obesity , biology , glycoprotein , microbiology and biotechnology
Fetuin-A, a glycoprotein with anti-inflammatory properties, plays an important role in counter-regulating inflammatory responses. It has also been associated with insulin resistance and metabolic syndrome. We aimed to investigate circulating concentrations of fetuin-A and its possible association with hepatic and systemic inflammation in nondiabetic subjects with nonalcoholic fatty liver disease (NAFLD).