Open AccessPepsin and bile acid concentrations in sputum of mustard gas exposed patients
Author(s) -
Ashraf Karbasi,
Hassan Goosheh,
Rasoul Aliannejad,
Hamid Reza Saber,
Maryam Salehi,
Mahtab Jafari,
Saber Imani,
Amin Saburi,
Mostafa Ghanei
Publication year - 2013
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.111954
Subject(s) - sputum , medicine , pepsin , gastroenterology , bronchiolitis obliterans , sulfur mustard , asthma , respiratory system , gerd , airway , reflux , lung , pathology , surgery , enzyme , biochemistry , tuberculosis , disease , chemistry , lung transplantation , toxicity
Gastro-esophageal reflux has been suggested to be associated with several pulmonary complications such as asthma, and post-transplant bronchiolitis obliterans (BO). Pepsin or bile salts in the sputum is shown to be an optimal molecular marker of gastric contents macro/micro aspiration. In this study, we investigated sputum pepsin as a marker of micro-aspiration in sulfur mustard (SM) exposed cases compared to healthy controls.