Open AccessDo probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy?
Author(s) -
Asad Izziddin Dajani,
Adnan M. Abu Hammour,
Ding H Yang,
PeiHua Chung,
Mohamed Ismail Nounou,
Kaitao Yuan,
Mohammed A. Zakaria,
Hanping S Schi
Publication year - 2013
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.111953
Subject(s) - medicine , clarithromycin , regimen , helicobacter pylori , metronidazole , amoxicillin , probiotic , gastroenterology , randomized controlled trial , antibiotics , microbiology and biotechnology , bacteria , biology , genetics
The standard triple therapy for the eradication of Helicobacter pylori consists of a combination of a proton pump inhibitor at a standard dose together with two antibiotics (amoxicillin 1000 mg plus either clarithromycin 500 mg or metronidazole 400 mg) all given twice daily for a period of 7-14 days. Recent reports have shown a dramatic decline in the rate of H. pylori eradication utilizing standard triple therapy from 95% down to 70-80%.