Open AccessHepatitis C genotype 4: Genotypic diversity, epidemiological profile, and clinical relevance of subtypes in Saudi Arabia
Author(s) -
Hamad Ibrahim Al Ashgar,
Mohammed Q. Khan,
Mohammed N. Al-Ahdal,
Sahar Al Thawadi,
Ahmad Helmy,
Ahmed A. Al-Qahtani,
Faisal M. Sanai
Publication year - 2013
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.105920
Subject(s) - medicine , ribavirin , genotype , hepatitis c virus , transmission (telecommunications) , pegylated interferon , hepatitis c , epidemiology , etiology , gastroenterology , immunology , virology , virus , biology , gene , biochemistry , electrical engineering , engineering
Hepatitis C virus genotypes 4 (HCV-4) is the most prevalent genotype in Saudi Arabia, although it's various subtypes, mode and route of transmission remains unknown. The aim of this study was to analyze (i) the variability of the HCV-4 subtypes, the route and source of HCV transmission and (ii) the influence of HCV-4 subtypes on their therapeutic response.