Open AccessMycophenolate mofetil associated with progressive multifocal leukoencephalopathy with successful outcome
Author(s) -
Driss El Kabbaj,
Mehdi El Hassani,
Mouncif Kadiri,
J. Mounach,
H. Ouhabi,
C. Haimeur,
Zouhir Oualim
Publication year - 2012
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.98162
Subject(s) - medicine , mycophenolate , discontinuation , progressive multifocal leukoencephalopathy , coma (optics) , leukoencephalopathy , pediatrics , mycophenolic acid , neurological deficit , drug , surgery , multiple sclerosis , disease , pharmacology , transplantation , immunology , physics , optics
The use of mycophenolate mofetil (MMF) is known to be associated with progressive multifocal leukoencephalopathy (PML). We report a case of PML in a patient receiving MMF, who showed improvement upon discontinuation of the drug. He was restarted on MMF, following which he went into coma. He showed prompt recovery upon stopping the drug again and made full recovery without any residual neurological deficit. This case is being reported to further highlight this neurological side-effect of MMF.