Mycophenolate mofetil associated with progressive multifocal leukoencephalopathy with successful outcome | Zendy

Driss El Kabbaj | Zendy; Mouncif Kadiri | Zendy; H. Ouhabi | Zendy; Zouhir Oualim | Zendy; Mohammed Hassani | Zendy; J. Mounach | Zendy; C. Haimeur | Zendy

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Mycophenolate mofetil associated with progressive multifocal leukoencephalopathy with successful outcome

Author(s) -

Driss El Kabbaj,

Mouncif Kadiri,

H. Ouhabi,

Zouhir Oualim,

Mohammed Hassani,

J. Mounach,

C. Haimeur

Publication year - 2012

Publication title -

saudi journal of kidney diseases and transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 30

eISSN - 2320-3838

pISSN - 1319-2442

DOI - 10.4103/1319-2442.98162

Subject(s) - medicine , mycophenolate , discontinuation , progressive multifocal leukoencephalopathy , coma (optics) , leukoencephalopathy , pediatrics , mycophenolic acid , neurological deficit , drug , surgery , multiple sclerosis , disease , pharmacology , transplantation , immunology , physics , optics

The use of mycophenolate mofetil (MMF) is known to be associated with progressive multifocal leukoencephalopathy (PML). We report a case of PML in a patient receiving MMF, who showed improvement upon discontinuation of the drug. He was restarted on MMF, following which he went into coma. He showed prompt recovery upon stopping the drug again and made full recovery without any residual neurological deficit. This case is being reported to further highlight this neurological side-effect of MMF.

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