Open AccessMesalazine induced focal segmental glomerulosclerosis in a patient with ulcerative colitis
Author(s) -
Fatih Yılmaz,
Bora Uslu,
Bahar Akkaya,
Ramazan Çetinkaya
Publication year - 2020
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.284031
Subject(s) - mesalazine , medicine , ulcerative colitis , focal segmental glomerulosclerosis , aminosalicylic acid , nephrotic syndrome , renal biopsy , gastroenterology , renal function , glomerulosclerosis , biopsy , urology , colitis , glomerulonephritis , proteinuria , kidney , disease
Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis applied to doctor due to swelling in the lower extremities. The patient was diagnosed with nephrotic syndrome (NS). Renal biopsy was performed, and FSGS was diagnosed. Antiproteinuric treatments were initiated with steroid therapy. The patient has been followed with the normal renal function of the after treatment. 5-aminosalicylic acid derivatives affect renal functions at different levels and caused in NS.