Open AccessUnusual presentation of systemic lupus erythematosus
Author(s) -
Mahesh Eswarappa,
Parampalli Rakesh Madhyastha,
Vijay Varma,
KC Gurudev,
Gireesh,
Sujeeth Reddy Bande
Publication year - 2017
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.206468
Subject(s) - medicine , lupus nephritis , antibody , immunology , dermatology , nephritis , lupus erythematosus , pathology , presentation (obstetrics) , systemic disease , immunopathology , disease , radiology
Bullous systemic lupus erythematosus is a rare distinctive subepidermal blistering disorder that can occur in patients with systemic lupus erythematosus (SLE). It is histologically characterized by a neutrophil-predominant infiltrate in the subepidermal region with deposition of immunoglobulins (IgG, IgA, IgM), C3, and auto-antibodies against collagen VII. Herein, we report a case of a 13-year-old girl who presented with bullous SLE and Class III lupus nephritis, which is extremely rare at this age.