Open AccessCarnitine reduced erythropoietin dose required and improved cardiac function of patients on maintenance hemodialysis
Author(s) -
Yosuke Aoki,
Takako Yamamoto
Publication year - 2017
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.206445
Subject(s) - medicine , erythropoietin , carnitine , ejection fraction , hemodialysis , darbepoetin alfa , transferrin saturation , cardiac function curve , hemoglobin , cardiology , maintenance dose , transferrin , brain natriuretic peptide , urology , endocrinology , heart failure , anemia , iron deficiency
Intravenous administration of 2 g carnitine in every hemodialysis (3 times/week), for 8-10 months, reduced doses of darbepoetin alfa required to maintain adequate hemoglobin levels (10-11 g/dL) into 10% of the initial doses. There was also a significant increase in plasma transferrin saturation, increase in left ventricular ejection fraction, and decrease in plasma brain natriuretic peptides.