Open AccessEffect of pediatric liver transplantation on renal function
Author(s) -
Hasan M Isa,
Afaf Mohamed,
Amer Alderazi
Publication year - 2016
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.174041
Subject(s) - medicine , renal function , liver transplantation , transplantation , incidence (geometry) , hepatic dysfunction , liver dysfunction , intensive care medicine , disease , urology , renal transplant , physics , optics
The aim of this review is to define the incidence of renal dysfunction among pediatric liver transplant (LT) survivors, to identify the associated risk factors and to outline the therapeutic options. Renal dysfunction is a common problem after pediatric LT. The measured glomerular filtration rate is considered the "gold-standard" for assessment of renal function. Renal dysfunction in pediatric LT recipients is multifactorial. Renal-sparing immunosuppressive strategies are essential to reverse renal dysfunction and to prevent end-stage renal disease.